Name
JoAnn C.L. Schuh
Educational Degrees
BS, DVM, MS, PhD
Certifications
DABT - Diplomate American Board of Toxicology, DACVP - Diplomate American College of Veterinary Pathologists
Education
PhD, Veterinary Pathology, University of Saskatchewan
MS (Veterinary Science), University of Wisconsin
DVM, University of Saskatchewan
BSc, University of Alberta
Dip. Bus. Admin., Wilfred Laurier University
Expertise
Biologics/Biotherapeutics/Biotechnology, Carcinogenicity, Cardiovascular Toxicology, Dermal Toxicology, Drug/Pharmaceutical Development, Hematologic Toxicology, Hepatic Toxicology, Immunotoxicology, Medical Devices, Nanotoxicology, Ocular Toxicology, Pharmacokinetics/Toxicokinetics, Regulatory Toxicology, Renal Toxicology, Risk Assessment, Safety Pharmacology, Toxicologic Pathology
Specialties
Therapeutics:
• Immunotherapeutics
• Ocular therapeutics
• Metabolic therapeutics
• Signaling molecules
• Medical devices and combination products
• Photodynamic therapy (PDT)
• Embolotherapy
Organ/Tissue Expertise:
• Immune system and lymphoid tissues
• Hematopoietic system
• Special senses - eye and ear
• Musculoskeletal system - bone, cartilage, teeth, skeletal muscle
• Mucosal surfaces
• Integument system (skin)
• Infectious Diseases (spontaneous and induced)
• Tumor models
• Genetically engineered (modified) animal phenotyping
Toxicology:
• Development of biologics, biosimilars and biobetters
• Development of small molecules
• Development of oncology therapeutics and immunotherapeutics
• Development of monoclonal antibodies
• Development of molecular-based therapeutics - siRNA, oligonucleotides
• Development of small molecules
• Development of medical devices and combination products
• Development of nanotechnology products
• Regulatory representation and summaries
• Expert reviews
• GLP study monitoring
Efficacy study design and evaluation:

• Animal models of inflammation and auto-immunity
• Animal models for oncology
• Animal models for ocular diseases
• Animal models of wound healing
• Animal models for medical devices
• Animal models of human disease
• In vivo pharmacology and efficacy study design and evaluation
Safety pharmacology study evaluation
Histopathology:
• Immune system and lymphoid tissues
• Hematopoietic system
• Special senses - eye and ear
• Hard tissues - bone, cartilage, teeth
• Mucosal surfaces
• Tumors
• Immunohistochemistry
• Tissue cross-reactivity studies
• Expert reviews, peer review and tumor reviews
• Clinical pathology evaluations
Corporate Goverance:
• Member of corporate scientific advisory committees
• Due diligence for corporate acquisitions

Financial Sector Consulting:
• Nonclinical and preclinical research and development
• Toxicology and Pathology reviews of pharmaceuticals, small molecular, biologics and medical devices
• Animal models of disease
• Pathophysiology in comparative medicine
Experience
Independent consultant since 2000
25 years of practice in toxicology development, regulatory submissions and toxicologic pathology evaluations
Previous employers include Warner-Lambert Parke-Davis (now Pfizer) and Immunex Corp (now Amgen)
City
Bainbridge Island
State
WA
Zip Code
98110-3663
Country
USA
Telephone
206-295-4944