Name
Leanne Bedard
Educational Degrees
PhD
Certifications
DABT - Diplomate American Board of Toxicology
Education
MSc in Chemistry, Carleton University, Ottawa, ON Canada
PhD in Pharmacology and Toxicology, Queen's University, Kingston, ON, Canada
Certified in Regulatory Affairs (RAC)
Expertise
Drug/Pharmaceutical Development, In Vitro Toxicology, Pharmacokinetics/Toxicokinetics, Regulatory Toxicology, Risk Assessment
Specialties
- Problem-solving of absorption, distribution, metabolism and excretion (ADME) and toxicology issues in lead compounds and series in drug discovery
- Design and data interpretation of nonclinical ADME, pharmacokinetic/toxicokinetic, and toxicology studies
- Projections of human pharmacokinetic parameters based on nonclinical data
- Projections of human efficacious dose based on nonclinical pharmacokinetics and pharmacodynamics
- Risk assessment of drug-drug interaction potential using mathematical models
- Preparation and/or review of nonclinical pharmacokinetic and toxicology sections for regulatory submissions
- Messaging of study findings for communication to regulatory authorities
- Interfacing/interacting with regulatory authorities for filings in jurisdictions worldwide
Experience
Drug discovery experience in several therapeutic areas, such as respiratory diseases, infectious diseases (HIV, HCV), chronic pain, CNS disorders, rare/orphan diseases, inflammation and oncology.
Work experience in 2 large pharmaceutical companies: DMPK Drug Design Leader, AstraZeneca R&D Montreal; Senior Research Chemist, Preclinical Drug Metabolism and Pharmacokinetics, Merck Frosst Centre for Therapeutic Research.
Recipient of a Merck Frosst Discovery and Preclinical Sciences Special Achievement Award for significant contribution to the discovery of PIFELTRO, now marketed for the treatment of HIV-1
Councilor for Industry, Board of Directors of the Society of Toxicology of Canada (2009-2012).  
Adjunct Assistant Professor, Department of Biomedical and Molecular Sciences, Queen's University (2007-present).  
Councilor, Drug Discovery Toxicology Specialty Section, Society of Toxicology (2014-present).
Expert Scientific Advisor to TPD, Health Canada (2012-present).
Address
Bedard ADME-Tox Solutions
City
Kirkland
State
QC
Zip Code
H9J 1N2
Telephone
514-258-3382